A recent study showed that, when administered during pregnancy, infliximab takes longer to clear an infant’s system than adalimumab…
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Opinion: Erosive Changes Questioned in RA/Lupus Overlap Syndrome
I read with interest the Diagnostic View (TR, April), which, according to the authors, represented a case of rhupus, an overlap syndrome of RA and SLE. I challenge this view. My arguments: In the case of erosive RA, typically erosive changes are seen at MTP joints other than MTP1 (e.g., MTP5). In addition, the erosive…
Rheumatoid Arthritis & Autoimmune Glomerulonephritis
Rheumatoid arthritis (RA) is rarely associated with renal manifestations, but secondary amyloidosis due to chronic inflammation is reported to be the etiology of renal dysfunction in many cases of RA.1,2 The discovery of biologic therapy, with TNF-alpha inhibitors in particular, made a huge difference in the disease course and prognosis of RA patients. However, TNF-alpha…
Christopher Ritchlin Balances Patient Care with Beekeeping Hobby
When Christopher Ritchlin, MD, MPH, isn’t teaching students, residents and fellows at the University of Rochester Medical Center (URMC), treating patients or conducting medical research in his lab, he’s monitoring the health of another sort of patient—honeybees. For the past four years. Dr. Ritchlin, professor and chief of allergy, immunology and rheumatology at URMC, has…
Rheumatology Drug Updates: Etanercept for Pediatric Plaque Psoriasis
Etanercept Submitted for Chronic, Severe Plaque Psoriasis in Children The U.S. Food and Drug Administration (FDA) has accepted the supplemental Biologics License Application for etanercept (Enbrel) for treating pediatric patients with chronic, severe plaque psoriasis.1 The application was submitted in early January 2016 and is based on results of a one-year Phase 3 study with…
ARHP Past Presidents Share Ties to Tucson, Arizona
The American College of Rheumatology (ACR) recognized the 50th anniversary of the Association of Rheumatology Health Professionals (ARHP) during the ACR/ARHP Annual Meeting this past November in San Francisco. The University of Arizona Arthritis Center followed up with a reception in Tucson to honor past presidents of the ARHP. The Tucson area has the highest…
Diagnostic Tests, Tips for Gluten-Induced Celiac Disease
CHICAGO—Celiac disease—the gluten-induced illness that can be seen alongside rheumatic diseases—has been seen much more commonly over the past 20 years than it was previously, but the illness can come with questions that are not always straightforward, an expert said at the ACR’s State-of-the-Art Clinical Symposium. The disease, in which the small intestine becomes inflamed…
Early Consults, Timely Patient Histories Aid Rheumatologists Treating Patients in the ICU
CHICAGO—When it comes to treating patients with rheumatic diseases who are in the intensive care unit (ICU), there are so many complications and considerations that few rules exist as a guide. But Paul Dellaripa, MD, associate professor at Harvard Medical School, said at the ACR’s State-of-the-Art Clinical Symposium that there are basic steps a rheumatologist…
Pitfalls of Potential Lupus Diagnosis
Spotting the signs of autoimmunity as early as possible is often viewed as a positive goal for rheumatologic research. The premise: Patients may begin treatment years before their disease is active and destroying joints and tissue. Although much progress has been made in identifying early stages of rheumatoid arthritis pathogenesis, the clues are not as…
Find Your Mentor in Medicine
Medicine has traditionally been an apprenticeship model. The most elemental and constructive method of passing on knowledge is the mentor–mentee relational experience. Mentorship encompasses not only the role of teacher, but also that of coach, role model, advisor and confidante. Matthew J. Koster, MD, rheumatology fellow and instructor in medicine, Mayo Clinic, Rochester, Minn., can…
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