A study found that litifilimab, a humanized monoclonal antibody that binds blood dendritic cell antigen 2, may be effective for the treatment of patients with active cutaneous lupus erythematosus. The treatment successfully reduced skin disease activity in patients at 16 weeks compared with placebo.
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A Medical Research Career Fueled by Curiosity
In January, Cecilia Pilar Chung, MD, MPH, began her new appointment as director of the Division of Rheumatology at the University of Miami. Previously, Dr. Chung was an associate professor of medicine at Vanderbilt University, Nashville, Tenn., for more than 10 years. At Vanderbilt, Dr. Chung built a strong research portfolio, focusing on the comparative…
ACR Open Rheumatology Seeks New Editors
As ACR Open Rheumatology (ACROR) enters its fifth year, its founding editors in chief are looking back on the journal’s accomplishments and forward to ushering in a new era, beginning with a search for their successors. Patricia Katz, PhD, professor of medicine and health policy at the University of California, San Francisco (UCSF), and Edward…
Research Update: Using Vagus Nerve Stimulation for Rheumatic Disease
Over the past decade, a number of pilot studies have provided proof of concept for the use of vagus nerve stimulation (VNS) to treat rheumatic conditions. The studies represent an expansion of this treatment approach into rheumatology, building on years of scientific inquiry into the mechanisms of VNS on disease states that led to preclinical…
Insights from a Neuro-Rheumatology Clinic
Neuro-rheumatology is a fast-growing field. Better testing and imaging have increased recognition of once-infrequent diagnoses, such as neuro-sarcoidosis and amyloid beta-related angiitis. Concurrently, the rapid expansion of immunotherapy options to treat cancer and their untoward neurological side effects have increased the frequency of referrals to both neurologists and rheumatologists. Identifying and treating neurologic manifestations of…
Mark Cuban: Mixing Up the Pharmaceutical Landscape
The Mark Cuban Cost Plus Drug Co. (CPD) launched in January 2022 to distribute and home deliver prescribed generic medications to consumers. The Texas-based business seeks to reduce the prices of generic drugs by leapfrogging financial negotiators and going straight to drug companies for supply, according to a news release.1 “It’s crazy that medications are…
Case Report: GPA or IgG4-Related Disease in an 11-Year-Old Girl?
Granulomatosis with polyangiitis (GPA) is a type of anti-neutrophil cytoplasmic antibody (ANCA) associated small vessel vasculitis that typically affects the kidneys, lungs and sinuses.1 Due to an overlap in signs and symptoms, GPA may initially be difficult to distinguish from IgG4-related disease, another condition that can affect multiple tissues and has variable presentations. Further complicating…
Tips to Alleviate Rheumatologist Burnout
Because rheumatology is a complex cognitive specialty, rheumatologists and rheumatology professionals often see patients repeatedly for acute and chronic problems. Although that may lead to close relationships with patients, it may also make the specialty more prone to burnout, says Peter Y. Hahn, MD, MBA, CEO of University of Michigan Health-West, Wyoming, Mich. “It can…
Appreciative Rheumatology: Positivity Beyond Serologies
Spam, spam, advertisement, spam … wait wait, what’s this? A small envelope, addressed from Maine. I wonder what this is about? Usually, when I get an envelope this size, it’s a letter from someone trying to sell me something or complain about something I have no control over. So imagine my surprise when I found…
A Unique Partnership Gives the ACR a Voice in Insurance Legislation Development
A recent meeting of the National Council of Insurance Legislators (NCOIL) featured discussions of many topics important to ACR members, including pharmacy benefit manager legislation, biomarker testing and transparency in the healthcare market.
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