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Clinical Insights into Axial Spondyloarthritis: Rheumatology Drugs at a Glance, Part 5

Mary Choy, PharmD, BCGP, FASHP  |  February 10, 2022

Over the past few years, biosimilars and other new drugs have been introduced to treat rheumatic illnesses. Some of the conditions we treat have numerous drug options; others have few or only off-label options. This series, Rheumatology Drugs at a Glance, provides streamlined information on the administration of biologic, biosimilar and other medications used to…

Filed under:Axial SpondyloarthritisBiologics/DMARDsConditionsDrug Updates Tagged with:Ankylosing SpondylitisAS Resource Center

Targeting Disease-Causing Cells: RheumMadness 2022 Chimeric Antigen Receptor T Cells Scouting Report

Mass General Hospital Rheumatology Fellowship Program: Guy Katz, MD; Ian Cooley, MD; Duncan Moore, MD; Jacquelyn Nestor, MD, PhD; & Steven Witte, MD, PhD  |  February 8, 2022

CD19 chimeric antigen receptor T (CAR-T) cell therapies may have the potential to treat rheumatic diseases in which current therapeutic options are limited, such as lupus, interstitial lung disease and systemic sclerosis.

Filed under:ConditionsResearch Rheum Tagged with:CAR-T cell therapycellschimeric antigen receptor T (CAR-T) cellsRheumMadness

Order in the Inflammatory Mess: RheumMadness 2022 Cytokine Networks Scouting Report

Rheumatology Leadership Team: David Leverenz, MD; Akrithi Udupa, MD; Guy Katz, MD; Lauren He, MD; Ben Kellog, MD; Michael Macklin, MD; Courtney Bair; Matthew Sparks, MD; & Lisa Criscione-Schreiber, MD, MEd  |  February 8, 2022

Research has identified and described a pro-inflammatory cytokine network shared by four rheumatic conditions that may be particularly active in patients with severe disease.

Filed under:Uncategorized Tagged with:cellscytokine networksCytokinesRheumMadness

Broadcasting Rheumatology Information to Wider Audiences

Kelly Tyrrell  |  February 3, 2022

Since starting the ACR on Air podcast in 2019, Mohammad Ursani, MD, FACP, RhMSUS, has become chair of the Committee on Communications and Marketing. Here, he shares some plans for the ACR website, podcast and more.

Filed under:American College of RheumatologyProfiles Tagged with:ACR Communications and Marketing CommitteeACR on Air podcastMohammad Ursani

Highlights from ACR Convergence’s Late-Breaking Abstracts

Samantha C. Shapiro, MD  |  February 2, 2022

COVID-19 vaccination, treatments for rheumatic disease and more—the Late-Breaking Abstracts session of ACR Convergence 2021 highlighted six studies with implications for rheumatology.

Filed under:ACR ConvergenceMeeting ReportsResearch Rheum Tagged with:ACR Convergence 2021COVID-19emapalumabgiant cell arteritis (GCA)Researchrituximabsecukinumabvaccines

How Do Axial SpA & PsA with Axial Involvement Differ?

Samantha C. Shapiro, MD  |  February 2, 2022

The differences between axial spondyloarthropathy (axSpA) and axial involvement in psoriatic arthritis (axPsA) have clinical and therapeutic implications. Three experts discussed the distinctions during ACR Convergence 2021.

Filed under:ACR ConvergenceAxial SpondyloarthritisConditionsMeeting ReportsPsoriatic Arthritis Tagged with:ACR Convergence 2021axial spondyloarthritis (SpA)axial spondyloarthropathyPsoriatic Arthritis

New Data Highlight Effectiveness of Guselkumab for Patients with PsA

Michele B. Kaufman, PharmD, BCGP  |  February 2, 2022

The use of guselkumab improved joint and skin symptoms in biologic naive patients with PsA, according to research presented during ACR Convergence 2021.

Filed under:ACR ConvergenceDrug UpdatesMeeting Reports Tagged with:ACR Convergence 2021guselkumabPsAPsoriatic Arthritis

Tigulixostat Appears Promising for the Treatment of Gout

Michele B. Kaufman, PharmD, BCGP  |  February 2, 2022

In a phase 2 study, tigulixostat treatment proved safe for lowering serum uric acid (sUA) levels in patients with gout.

Filed under:ACR ConvergenceConditionsDrug UpdatesGout and Crystalline ArthritisMeeting Reports Tagged with:ACR Convergence – GoutACR Convergence 2021ACR Convergence 2021 – GoutGoutserum uric acidtigulixostat

FDA Approves Secukinumab for Children with Enthesitis-Related Arthritis & PsA

Michele B. Kaufman, PharmD, BCGP  |  February 2, 2022

The FDA has approved the use of secukinumab for pediatric patients with enthesitis-related arthritis and psoriatic arthritis, after research showed a longer time to disease flare than placebo.

Filed under:ConditionsDrug UpdatesPediatric Conditions Tagged with:enthesitis-related arthritis (ERA)FDAFDA approvalPediatricPediatric RheumatologyPsAPsoriatic ArthritissecukinumabU.S. Food and Drug Administration (FDA)

The Ins & Outs of ILD: The Management & Treatment of ILD in Patients with Rheumatic Disease

Lara C. Pullen, PhD  |  February 2, 2022

Melissa Griffith, MD, discussed the diagnosis and treatment of interstitial lung disease (ILD) in patients with rheumatic diseases, including connective tissue disease and more.

Filed under:ACR ConvergenceConditionsMeeting Reports Tagged with:ACR Convergence 2021connective tissue diseaseILDinterstitial lung disease (ILD)pneumoniaRheumatoid Arthritis (RA)Sclerodermascleroderma-associated ILD

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