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Search results for: hospital

COVID-19 Vaccination Strategies Suggested for Patients on Anti-Rheumatic Immunosuppressive Therapy

Marilynn Larkin  |  March 29, 2021

NEW YORK (Reuters Health)—U.K. experts propose evidence-based management strategies for rheumatology patients on immunosuppressive therapy, including delaying/postponing rituximab, as appropriate. “The aim of this viewpoint article is to outline the existing data on the effect of anti-rheumatic therapy on vaccine responses in patients with inflammatory arthritis and to formulate a possible pragmatic strategy for the…

Filed under:Conditions Tagged with:COVID-19immunosuppressive therapyrituximabU.K.vaccination

FDA Approves Tocilizumab to Treat Systemic Sclerosis-Associated ILD

Michele B. Kaufman, PharmD, BCGP  |  March 25, 2021

Subcutaneous tocilizumab is the first biologic agent approved by the FDA treat patients with systemic sclerosis-associated interstitial lung disease.

Filed under:Drug Updates Tagged with:FDAFDA approvalILDinterstitial lung disease (ILD)systemic sclerosis (SSc)systemic sclerosis-associated ILDtocilizumabU.S. Food and Drug Administration (FDA)

Non-Invasive Vagus Nerve Stimulation Tolerated, Effective for Rheumatoid Arthritis

Lisa Rapaport  |  March 24, 2021

(Reuters Health)—Non-invasive vagus nerve stimulation is safe and effective as an intervention for rheumatoid arthritis (RA), a small proof-of-concept study suggests. The study enrolled 35 patients with active RA and an inadequate response to therapy with disease-modifying anti-rheumatic drugs (DMARDs). All DMARDS were discontinued four weeks prior to the trial. For the study, all participants…

Filed under:ConditionsRheumatoid Arthritis Tagged with:Rheumatoid Arthritis (RA)vagus nerve stimulation

FDA Approves Belimumab & Voclosporin for Lupus Nephritis

Michele B. Kaufman, PharmD, BCGP  |  March 24, 2021

In December, the FDA approved belimumab, the first drug approved to treat lupus nephritis, an historic action that was rapidly followed in January by the approval of a second treatment for lupus nephritis, voclosporin.

Filed under:ConditionsDrug UpdatesSystemic Lupus Erythematosus Tagged with:belimumabFDAFDA approvalLupus nephritisU.S. Food and Drug Administration (FDA)voclosporin

Improving Demographic Representation & Equity in Rheumatology Research

Allison Plitman  |  March 18, 2021

A better understanding of knowledge gaps and increased engagement of underrepresented communities are needed to diversify rheumatology patient data in clinical datasets, registries and randomized clinical trials.

Filed under:Information TechnologyResearch RheumSystemic Lupus ErythematosusTechnology Tagged with:Clinical researchdemographicsDiversityRheumatology Informatics System for Effectiveness (RISE) Registry

COVID-19 Vaccination for Immunosuppressed Patients: From Guidance to Advocacy

Joseph Cantrell, JD  |  March 18, 2021

State-level wins that ensure immunosuppressed patients can access COVID-19 vaccination show the power of coordinated efforts by volunteer leaders, staff and members to translate the ACR’s work into actionable public policy recommendations, then amplify those messages through member engagement.

Filed under:American College of RheumatologyLegislation & Advocacy Tagged with:ACR advocacyCOVID-19state societyvaccination

Autoantibodies Against LINE-1 p40 May Be More Common in Patients with Active SLE

Vanessa Caceres  |  March 17, 2021

Researchers found nearly all systemic lupus erythematosus (SLE) patients have autoantibodies against long interspersed nuclear elements (LINE-1) p40. These findings suggest LINE-1 may be involved in the pathogenesis of SLE.

Filed under:ConditionsSystemic Lupus Erythematosus Tagged with:autoantibodiesSLE

New Clinical Trials for Ustekinumab & Denosumab Biosimilars Begin Recruitment

Michele B. Kaufman, PharmD, BCGP  |  March 17, 2021

Clinical trials of biosimilar treatments, including a phase 1 study of SB17, which is biosimilar to ustekinumab, and two phase 3 studies investigating of SB16, which is biosimilar to denosumab, are currently recruiting.

Filed under:Biologics/DMARDsDrug Updates Tagged with:Biosimilarsclinical trialsdenosumabSB17ustekinumab

Rheum After 5: Dr. Mehta, a Rheumatologist & Wheel of Fortune Winner

Carol Patton  |  March 15, 2021

Updated 12/20/2022 to add a video link to the episode. Fire truck. Those are among the favorite words of Jay Mehta, MD, a pediatric rheumatologist and rheumatology fellowship director at Children’s Hospital of Philadelphia.  When he was in high school, Jay appeared on the TV game show, Wheel of Fortune, during My Favorite Teacher week….

Filed under:ProfilesRheum After 5 Tagged with:Dr. Jay Mehta

Case Report: A Patient with Submandibular Swelling

Julia A. Ford, MD, Robert Padera, MD, PhD, & Lindsey A. MacFarlane, MD, MPH  |  March 15, 2021

We report on a 77-year-old patient who was diagnosed with giant cell arteritis (GCA) on histopathology of the submandibular gland and eventually went on to develop classic signs and symptoms of GCA. This observation highlights neck swelling as a rare initial presentation of GCA. Case Presentation A 77-year-old previously healthy man presented to his primary…

Filed under:ConditionsVasculitis Tagged with:case reportGiant Cell Arteritissubmandibular swelling

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