Science From Arthritis & Rheumatism
Within Our Reach–Funded Research Finds Highly Specific Markers of RA
A study recently published in Arthritis & Rheumatism concluded that anti–peptidyl arginine deiminase type 4 (PAD-4) antibodies are highly specific markers of RA and appear to be useful markers of disease severity. The project studied an important and previously unrecognized immune response in RA—anti–PAD-4, which is one of the major proteins that creates other common autoantigens in RA.