Lisa Christopher-Stine, MD, MPH, discussed the latest findings on myositis and its subtypes, including insights into antibodies linked to cancer and treatments for these patients.
How to Diagnose Antisynthetase Syndrome
Antisynthetase syndrome (AS) is strongly associated with the presence of antibodies to aminoacyl-transfer RNA (tRNA) synthetases (ARSs) that are implicated in the pathogenesis of myositis and interstitial lung disease (ILD). Antibodies against eight antisynthetases have been identified and are detected in 16–26% of patients with idiopathic inflammatory myopathies (IIM).1 Serum assays for five of these…
Fellow’s Forum Case Report: When Pulmonary Symptoms Point to Rheumatic Disease
A 48-year-old man with diffuse arthralgias and acute respiratory failure is diagnosed with antisynthetase syndrome
Fellow’s Forum Case Report: Diagnosing Antisynthetase Syndrome
A variable combination of interstitial lung disease, myopathy, fever, joint involvement, and mechanic’s hands characterize this systemic autoimmune syndrome