A new case series outlines the treatment and duration of symptoms of 10 patients experiencing the musculoskeletal manifestations of immune-related adverse events. Researchers found these symptoms may last for more than a year, but can generally be treated with low to moderate doses of corticosteroids…
Walking Ability of OA Patients Linked to Cardiovascular Risk
New research explores the association of the ability to walk and the risk of cardiovascular disease in OA patients compared with the general population. During the study, researchers recorded a six-minute walking distance and measured arterial stiffness of participants. The results: Even among younger people, OA patients could not walk as far as those in the general population. Also, arterial stiffness was inversely associated with walking distance, suggesting walking is important to the cardiovascular risk profile of OA patients…
SLE Patients May Not Receive Enough Cardiovascular Disease Assessment & Treatment
Systemic lupus erythematosus (SLE) is associated with high rates of cardiovascular disease. However, research has shown that aggressive risk assessment with lipid screenings and treatment with statins may be suboptimal for these patients. A new study compared the rates of screening and treatment between SLE patients, diabetes mellitus patients and the general Medicaid population. The results: Despite having an elevated risk of CVD, SLE patients received less lipid testing and fewer statin prescriptions than other patients…
Low Muscle Density & Physical Function in Patients with RA
Low muscle density due to the accumulation of intramuscular fat has been observed in RA patients and is associated with higher disease activity. New research sought to understand the relationship between muscle density, physical function and strength independent of body composition, including such factors as total and visceral adiposity. The results: Compared with healthy controls, low muscle density in RA patients was associated with low muscle mass, excess adiposity and greater disability…
Is More Better? Weight Loss Analysis in Older Patients with Knee OA
Obesity is a modifiable risk factor for many patients with knee osteoarthritis (OA), and the National Institutes of Health recommend an initial weight loss goal of 10%. But how does losing more weight affect knee OA patients? In a new study, researchers compared the outcomes of knee OA patients who lost more and less than the recommended 10% of their baseline weight, finding significant improvement in health-related quality of life and reduction in pain for patients who lost twice what’s recommended…
Physical & Cognitive Function in SLE Patients
New research used multidomain function assessment to better understand the physical and cognitive functioning of systemic lupus erythematosus (SLE) patients. The pilot study found a high prevalence of impairment in SLE patients, similar to or exceeding the prevalence seen in the general geriatric population. Patients scored lower for lower body strength and low average for cognitive flexibility and attention…
Insight into Endothelial Dysfunction in Early SLE Patients without Cardiovascular Disease
The early identification of endothelial dysfunction may be useful in clinical practice to prevent SLE patients from developing atherosclerosis and cardiovascular disease. New research evaluated the use of peripheral arterial tonometry in assessing endothelial dysfunction in patients with early SLE and no cardiovascular risk factors or disease. The results: These patients showed a high rate of endothelial dysfunction and vascular stiffness…
Effects of Obesity on Sustained Remission in Early RA
A new study examined the independent effects of excess weight and obesity on achieving sustained remission in rheumatoid arthritis (RA) patients. Researchers found that within three years of RA diagnosis, overweight and obese patients were significantly less likely to achieve sustained remission than patients with healthy body mass indices (BMIs). Higher BMIs were also associated with persistent disease activity…
Program May Prevent Work Loss for Patients with Rheumatic Diseases
Within 10 years of diagnosis, 23–45% of patients with rheumatic and musculoskeletal disease may become unemployed due to disease-related disability. Intervention programs may be necessary to prevent this work loss. New research examined if a vocational rehabilitation program delivered by occupational and physical therapists can benefit this patient population…
Larger Weight Loss Tied to Greater Improvements in Arthritic Knees
(Reuters Health)—Obese people with knee osteoarthritis (OA) may find greater symptom relief when they lose larger amounts of weight, a recent study suggests. Researchers examined data on 240 obese adults with pain from knee OA who were participating in an 18-month experiment to see how diet alone or diet plus exercise affected their health. Participants…
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