Early Data on Novel MK2 Inhibitor to Treat Inflammatory Diseases Promising Michele B. Kaufman, PharmD, BCGP | June 9, 2022In a small preliminary study, the novel MK2 inhibitor, CC-99677, was safe and well tolerated by healthy participants. With daily dosing, the agent sustained reductions of tumor necrosis factor alpha and other cytokines for 14 days.