The FDA is strengthening its warning that canagliflozin and dapagliflozin may increase the risk for acute kidney injury in some patients. Also, the FDA has issued a warning that patients should not exceed recommended doses of loperamide due to increased risks of serious cardiac events…
Tofacitinib Promising for Psoriatic Arthritis & FDA Issues Alert for Warning for Saxagliptin & Alogliptin Diabetes Treatments
A recent Phase 3 study found tofacitinib safe and effective for treating psoriatic arthritis at both 5 mg and 10 mg doses compared with placebo. And the FDA has added label warnings to saxagliptin and alogliptin for an increased risk of heart failure in individuals taking the drugs, particularly in those with heart and kidney disease…
Health Apps Often Lack Privacy Policies & Share Our Data
(Reuters Health)—Just because a health app has a privacy policy doesn’t mean the data will remain private, an analysis of mobile tools for diabetes suggests. In fact, privacy policies appear rare, and when they do exist, most state that user data will be collected and half warn that medical information will be shared with third…
Early Probiotics Supplementation Tied to Lower Risk of Islet Autoimmunity
NEW YORK (Reuters Health)—Exposure to probiotics in the first few weeks of life is associated with a reduced risk of islet autoimmunity, according to results from the TEDDY study. “Early supplementation of probiotics may be important but we need more research on this,” Dr. Ulla Uusitalo from University of South Florida in Tampa told Reuters…
FDA Issues Warning for Joint Pain from Diabetes Drugs
Severe and disabling joint pain has been connected to the use of dipeptidyl peptidase-4 inhibitors and combination therapies for diabetes, prompting a new FDA warning…
Screen Type 1 Diabetes & Pediatric Rheumatology Patients for Celiac Disease
NEW YORK (Reuters Health)—Screening for celiac disease (CD) is important in patients newly diagnosed with type 1 diabetes (T1D) and in children presenting for rheumatology evaluation, according to a pair of new reports. In a systematic review, online June 15 in Pediatrics, Australian researchers found most cases of CD are diagnosed within five years of…
Metabolic Syndrome Linked to Higher Risk for Immunological Disorders
Research suggests patients with metabolic disorders, such as diabetes, might benefit from antiinflammatory drugs used to treat immunlogical disorders
Bariatric Surgery May Help Obese Patients with Gout, Diabetes
Researchers found patients with morbid obesity, gout and diabetes achieved target serum urate concentrations post-bariatric surgery
Dermatology Case Review
A 64-year-old man with history of type-II diabetes (well controlled on sitagliptin/metformin), hypertension, and dyslipidemia presents with complaints of an increasingly painful left lower-extremity lesion present for two to three months.