Recent research investigated the progression and characteristics of Sjögren’s syndrome using mice engineered to lack special genome organizing AT-rich sequence binding protein-1 (SATB1). These mice proved to be a novel model for Sjögren’s syndrome and revealed T cell-dominant immune cell infiltration of the salivary glands. Over time, the frequency of B cells gradually increased, as well as the levels of anti-SSA and anti-SSB antibodies…
Anemia is common in patients with systemic rheumatic disease, yet it may not get the attention it deserves. Anemia can result from chronic inflammation, treatment side effects or other disease factors, or it may signal an unrelated condition. Although diagnosis and treatment of anemia are sometimes challenging, clinicians must do their utmost to rigorously investigate…
Inside the pathophysiology, clinical presentations of chronic pruritus