NEW YORK (Reuters Health)—The anti-interleukin-17A monoclonal antibody secukinumab improves signs and symptoms in patients with psoriatic arthritis, according to results from Novartis’ FUTURE 2 trial. In earlier studies, secukinumab has demonstrated superior effectiveness to placebo and etanercept in improving the signs and symptoms of psoriasis. Dr. Iain B. McInnes from the University of Glasgow in…
Many Psoriasis Patients Have Undiagnosed Arthritis
(Reuters Health)—Up to 15% of people with psoriasis have undiagnosed arthritis that’s related to the skin condition, according to a new review. “The important takeaway,” said Dr. Abby Van Voorhees, director of the Psoriasis and Phototherapy Treatment Center at the Hospital of the University of Pennsylvania in Philadelphia, “would be that further education is needed…
Biosimilars for RA Studied in Multiple Trials
Biosimilars for etanercept and sarilumab are being examined in multiple Phase 3 trials for their effects in RA and psoriasis patients.
Ixekizumab Clinical Trials Continue; FDA Updates Warning Label for Varenicline
It seems to have begun in Norway, the international pressure to switch patients from well-known brand biologic agents, such as Remicade (infliximab), to biosimilar agents, due to a significant cost advantage.1 This biosimilar came with a 39% price markdown last year compared with the brand, and when Norway called for bids, the discount went to…
Clinical Trials Ongoing for Brodalumab
Brodalumab, an interleukin (IL) 17 inhibitor, is currently in early clinical trials (Phase 1b and Phase 2) for a number of different autoimmune diseases.1 Amgen recently terminated its co-development and commercialization agreement with AstraZeneca for the brodalumab investigational program in trials for moderate to severe plaque psoriasis, psoriatic arthritis and axial spondyloarthritis. Amgen’s decision to…
Psoriatic Arthritis: Recognize, Manage Comorbidities
As the literature on comorbidities linked to psoriatic arthritis (PsA) expands, it’s becoming more difficult for clinicians to keep up with what comorbidities should be assessed and how these comorbidities affect treatment selection. Given this, rheumatologists at the Perelman School of Medicine at University of Pennsylvania, Cleveland Clinic and Hospital for Special Surgery in New…
2014 ACR/ARHP Annual Meeting: Psoriatic Arthritis
Clinical manifestations, approaches to diagnosis, treatment
7 Tips That Dermatologists Want Rheumatologists to Know
Recommendations on diagnosing, treating health conditions that cross over both specialties
Occupational Therapy Can Benefit Rheumatology Patients
Patients often manage their condition better, perform daily activities with more ease with help from therapists
Diagnosis, Treatment for Patient with Psoriasis, Fever, Bloating, and Rash
A 65-year-old man presents with symptoms of erythrodermic psoriasis flare
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