AMP-activated protein kinase may be link between nutritional excess, inflammation that leads to gout
T Cells & Autoimmune Diseases
New investigational strategy provides way to identify, characterize autoreactive T cells that escape thymic selection and cause autoimmunity
Clues Emerge to Bone Health, Destruction in Rheumatoid Arthritis
Recent study identifies RBP-J signaling pathway as key regulator of osteoclastogenesis, bone remodeling
Cryopyrin-Associated Periodic Syndromes Affected by NLRP3 Mutation
Study links NLRP3 inflammasome with amplified, extracellular inflammatory response
Antiphospholipid Antibodies Activate mTORC in Vessels
Research around autoimmune disorder shows patients may respond to treatment with sirolimus
Metabolic Syndrome Linked to Higher Risk for Immunological Disorders
Research suggests patients with metabolic disorders, such as diabetes, might benefit from antiinflammatory drugs used to treat immunlogical disorders