Classification criteria for primary Sjögren’s syndrome (SS) have been approved by the American College of Rheumatology (ACR) and European League Against Rheumatism (EULAR), validating an international set of classification criteria for SS using standards set by both organizations. Those criteria can now be found in the 2016 ACR/EULAR Classification Criteria for Primary Sjögren’s Syndrome: A…
Dysbiosis of Gut, But Not Ocular Microbiome, Associated with Sjögren’s Syndrome
Research has explored the connection between Sjögren’s syndrome and intestinal dysbiosis associated with ocular mucosal disease. A recent study found that oral antibiotics and desiccating stress lead to extreme changes in the gut microbiota in mice. In patients with Sjögren’s syndrome, researchers found that patients with the most severe keratoconjunctivitis sicca and combined systemic and ocular disease had the lowest diversity of stool microbiota…
A Healthy Skepticism: Researchers Evaluate CNS Manifestations of Rheumatic Disease
SAN FRANCISCO—Let’s say your radiologist comes to you and says that an angiogram gives a diagnosis of CNS vasculitis on four patients, all with acute onset of headache and stroke: One is a 25-year-old woman who is three months pregnant. Another is a 50-year-old man using excessive doses of nasal decongestants. Another is a 40-year-old…
Sjögrens Syndrome: The Need to Bridge Patient Symptoms & Objective Findings
Despite a generation of advances in molecular biology, a huge gap exists between the Sjögren’s syndrome (SS) patient’s description of their symptoms and the objective findings. Current issues include: Many SS patients are misclassified as either rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE), even within rheumatology clinics. Frequently, the sickest SS patients with extraglandular…
2014 ACR/ARHP Annual Meeting: Sjögren’s Complications
Tips to screen for, treat central or peripheral nervous system disorders, lymphoma in patients with Sjögren’s syndrome
Atherosclerosis, Cardiovascular Disease More Common in Patients with Primary Sjögren’s Syndrome
Study adds to research linking increased risk of morbidity, early mortality from CV events among patients with systemic autoimmune diseases
Laboratory Testing for Diagnosis, Management of Patients with Rheumatic Disease
A review of data on antinuclear antibodies and tests for rheumatoid arthritis
The ACR: Looking Ahead to 2015 and Beyond
Incoming president E. William St.Clair, MD, sets goals, reviews groundwork for the coming year
Systemic Sjögrens: More Than a Sicca Disease
Differences in its epidemiologic, clinical and immunologic features underscore need for a homogeneous diagnostic and therapeutic approach
EULAR 2014: Ultrasound Use Important for Rheumatology
Experts offer insight into ultrasound for joint counts in rheumatoid arthritis, synovial biopsies, Sjögren’s syndrome
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