Recent breakthroughs in stem cell-based treatments for arthritis may help delay joint replacement for some patients. Farshid Guilak, PhD, described the methods for creating bioartificial cartilage, its implications for inflammation, disease flare and more.
Stem Cell Transplantation Benefits Patients with Scleroderma
A recently published study gives new insight into an innovative approach to treating patients with severe scleroderma and internal organ involvement. During the six-year study, researchers demonstrated the durability of the beneficial effects of stem cell transplantation in this patient population. Their data also suggest the treatment has the potential to renormalize the autoreactive immune system…
Mesoblast Cell Treatment Shows Promise in Rheumatoid Arthritis
(Reuters)—Mesoblast Ltd. on Monday said its experimental stem-cell treatment led to significant improvements of symptoms and disease activity in patients whose rheumatoid arthritis had stopped being helped by widely used biotech medicines, according to data from a mid-stage trial. Treatment with the Australian company’s mesenchymal precursor cell (MPC) product, MPC-300-IV, was deemed well tolerated with…
Careful Management Improves Safety of Stem Cell Transplantation in Crohn’s
NEW YORK (Reuters Health)—Careful use of antibiotics and corticosteroids can substantially improve the safety of autologous hematopoietic stem transplantation (HSCT) in patients with refractory Crohn’s disease (CD), researchers from Spain report. “Autologous HSCT is feasible but it is associated with severe adverse events and even mortality,” Dr. Elena Ricart from Hospital Clinic de Barcelona tells…
EULAR 2013: Researchers Make Inroads in Treatment of Osteoarthritis
Experts discuss evidence-based benefits of knee joint distraction and the progress being made in harnessing the effects of stem cells
ACR/ARHP Annual Meeting 2012: New Research Into Stem Cell Therapy and Drugs May Lead to Breakthrough Treatments for Osteoarthritis
Novel strategies for treating osteoarthritis aim to relieve pain, rebuild or replenish deteriorated cartilage and bone, or to replace the joint through surgery
The Forward View in Rheumatology
Future leaders convene at the ACR/Arthritis Foundation Rheumatology Research Workshop to discuss cutting-edge research and career development.
The Basic Science of the Annual Scientific Meeting
The ACR/ARHP Annual Scientific Meeting is the premier event for specialists in the field of rheumatology. At this year’s meeting, basic researchers will have multiple opportunities to increase their knowledge, and there will be something for every interest.
Progress Continues in Systemic Sclerosis
Advances in genetics and potential therapies shed new light on the disease
Th17 Cells Explained
The new kids on the block have rheumatologic ramificatons